The Digital revolution is profoundly transforming our society and business. Trust is at the core of our relationship with clients and other providers. It takes just one incident to destroy that relationship. Therefore, security is at the core of the digital transformation and the CISO is the key figure in safeguarding that trust. But how does one go about doing that? Where to start? As threats evolve and permutate, we have seen the evolution of a formerly overlooked player: the Chief Information Security Officer, or CISO. We will explore some of the issues that CISOs address in their strategic planning, the key ideas that help them prioritize the different issues they confront and navigate the uncertain threat landscape, the competitive pressures and the ever changing business environment.